KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK3
All Species:
19.09
Human Site:
S399
Identified Species:
38.18
UniProt:
P27448
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27448
NP_001122390.1
776
87005
S399
S
E
L
D
A
S
D
S
S
S
S
S
N
L
S
Chimpanzee
Pan troglodytes
XP_510184
737
82858
T360
K
Y
D
E
I
T
A
T
Y
L
L
L
G
R
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868647
777
86967
S400
S
E
L
D
A
S
D
S
S
S
S
S
N
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q03141
753
84371
S376
A
E
L
D
A
S
D
S
S
S
S
S
N
L
S
Rat
Rattus norvegicus
Q8VHF0
797
88733
S376
A
E
L
D
A
S
D
S
S
S
S
S
N
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508081
736
82480
S368
S
E
L
D
A
S
D
S
S
S
S
S
N
L
S
Chicken
Gallus gallus
Q9IA88
798
88848
N410
A
E
M
D
C
D
M
N
N
P
L
Q
P
V
F
Frog
Xenopus laevis
NP_001084256
725
81522
D372
G
R
K
S
S
E
L
D
A
S
D
S
S
S
S
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
G611
P
V
R
R
F
S
D
G
A
A
T
I
Q
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
K815
D
K
E
Q
Q
Q
Q
K
A
S
S
E
T
P
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
F184
C
N
V
K
I
A
D
F
G
L
S
N
I
M
R
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
A280
K
F
L
S
P
G
A
A
G
L
I
K
R
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
N.A.
96.4
N.A.
94
89.9
N.A.
90.5
31.4
85.6
26.5
N.A.
N.A.
N.A.
39.8
N.A.
Protein Similarity:
100
94.7
N.A.
97.4
N.A.
95
91.2
N.A.
92.9
50.7
89.5
42.6
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
100
0
N.A.
100
N.A.
93.3
93.3
N.A.
100
13.3
20
13.3
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
20
N.A.
100
N.A.
100
100
N.A.
100
46.6
40
33.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
42
9
17
9
25
9
0
0
0
9
0
% A
% Cys:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
50
0
9
59
9
0
0
9
0
0
0
0
% D
% Glu:
0
50
9
9
0
9
0
0
0
0
0
9
0
0
0
% E
% Phe:
0
9
0
0
9
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
9
0
0
0
0
9
0
9
17
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
17
0
0
0
0
0
9
9
9
0
0
% I
% Lys:
17
9
9
9
0
0
0
9
0
0
0
9
0
0
17
% K
% Leu:
0
0
50
0
0
0
9
0
0
25
17
9
0
42
9
% L
% Met:
0
0
9
0
0
0
9
0
0
0
0
0
0
17
0
% M
% Asn:
0
9
0
0
0
0
0
9
9
0
0
9
42
0
0
% N
% Pro:
9
0
0
0
9
0
0
0
0
9
0
0
9
9
0
% P
% Gln:
0
0
0
9
9
9
9
0
0
0
0
9
9
0
0
% Q
% Arg:
0
9
9
9
0
0
0
0
0
0
0
0
9
9
9
% R
% Ser:
25
0
0
17
9
50
0
42
42
59
59
50
9
9
50
% S
% Thr:
0
0
0
0
0
9
0
9
0
0
9
0
9
0
0
% T
% Val:
0
9
9
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _